Hola MDX08 Sample-to-Result PCR System
A compact sample-to-result PCR system for laboratories that want to run molecular testing with minimal manual handling. The system automates nucleic acid extraction, PCR set-up, amplification, and result interpretation for up to 8 samples per run.
Perfect for HLA testing in rheumatology
It allows laboratories and clinics to run HLA-B27, HLA-B51, HLA-DR4, and the HLA-DRB1 SE RA Risk Panel with very low hands-on time and fast turnaround.
Key features of the system
- Fully automated process including nucleic acid extraction and real-time PCR
- Up to 8 samples per run
- 90 seconds hands-on time per sample
- Results in 2 hours
- Reduced contamination risk through single-use consumables and closed handling steps
- Room-temperature shipping and storage of PCR reagents
- Designed for laboratories that want to reduce manual PCR steps or replace low-volume workflows
How it works
1. Prepare Extraction Plate & PCR Strip
2. Add Sample to Extraction Plate
3. Load Plate & PCR Strip into MDX08
4. Start Automated Run
Specifications
- Fully automated sample-to-result instrument with integrated touch screen
- Dimensions: 47 × 22.5 × 40 cm
- Weight: 13.8 kg
- Estimated annual capacity: up to 12,500 tests
- Time to result: approximately 2 hours
- Hands-on time: 90 seconds per sample
- Magnetic bead extraction technology
- Reagent management: pre-filled unit-dose deep-well format
- Sample volume: 200–400 µL
- Elution volume: 50–200 µL
- Wi-Fi, Bluetooth, USB
- Up to 8 samples per run
- Compatible sample matrices: whole blood, plasma, serum, cerebrospinal fluid, stool, urine, amniotic fluid, blood culture, nasal swab, throat swab, rectal swab, cervical swab
- Up to 5-plex target capability
- Compatible with the Hola Biolabs PCR portfolio
- Real-time PCR reaction volume: 20–50 µL
- Contamination control features: single-use consumables, filter tips, UV treatment
When this system makes sense
The MDX08 is designed for laboratories that want to reduce manual PCR handling or avoid building a complex molecular workflow. It is particularly relevant for sites introducing molecular testing, replacing send-out testing in selected applications, or simplifying an existing low-volume PCR set-up.
Ordering Information
| Product | Description | Quantity | Reference |
|---|---|---|---|
| Hola MDX08 System (4-color) | Sample-to-Result PCR System, 8-Sample Capacity, 4 Channels | 1 | HB802X08-4C |
| Hola MDX08 System (5-color) | Sample-to-Result PCR System, 8-Sample Capacity, 5 Channels | 1 | HB802X08-5C |
| Hola MDX08 NA Extraction Kit | Pre-filled Universal Extraction Deep-Well Plate | 32 | HB702X08-032 |
| Hola Real-time PCR Assays | Please refer to the PCR catalogue | ||
Compatible HLA PCR kits & consumables
The MDX08 is compatible with the full Hola Biolabs HLA PCR portfolio. The following kits are validated for use with the system:
HLA-DR4 PCR Kit
Lyophilized real-time SSP-PCR kit for qualitative detection of human HLA-DR4 (DRB1*04) alleles. Designed for HLA typing workflows with ambient-stable reagents and compatibility with selected open qPCR platforms or the Hola MDX08 System.
HLA-B51 PCR Kit
Lyophilized real-time SSP-PCR kit for qualitative detection of human HLA-B51 alleles from DNA extracted from peripheral blood. Designed for HLA-B51 typing workflows related to Behçet’s disease research, with internal control and compatibility with selected open qPCR platforms or Hola MDX08 automation.
HLA-B27 PCR Kit
Lyophilized real-time SSP-PCR kit for qualitative detection of human HLA-B27 alleles. Designed for HLA typing workflows with ambient-stable reagents and compatibility with selected open qPCR platforms or the Hola MDX08 System.
HLA-DRB1 Shared Epitope RA Risk Panel
PCR panel targeting key HLA-DRB1 markers associated with rheumatoid arthritis risk and severity, including Shared Epitope motifs, Val11, and DRB1*09:01.
Looking for a simpler way to run PCR testing?
Let's discuss whether the MDX08 fits your laboratory, application, and expected testing volume.
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