How to Broaden Your In-House HLA Portfolio
A practical route for laboratories already running PCR and looking to add relevant HLA markers in one set-up, with the option of full automation.
Why laboratories expand beyond HLA-B27
Many laboratories already running PCR offer only a limited HLA menu, often focused on HLA-B27. As clinical needs grow, this creates a gap between what the lab can deliver in-house and what clinicians request.
Hola Biolabs helps these laboratories expand their in-house HLA portfolio with lyophilized PCR kits that integrate easily into existing PCR set-ups or run with compact automation - without needing a completely new system for each marker.
What becomes possible when the HLA portfolio grows
Expand beyond a basic HLA menu
Introduce additional markers in-house and build a wider HLA offer.
One laboratory set-up
Run multiple HLA markers within the same workflow instead of managing separate processes for each test.
Offer a broader HLA menu for rheumatology-related requests
Provide clinicians with a more complete HLA menu aligned with rheumatology needs.
Key markers for portfolio expansion
- HLA-DRB1 SE RA Risk Panel: A focused RA panel combining Shared Epitope, Valine 11, and DRB1*09:01 in one test.
- HLA-B51: A useful addition for laboratories supporting testing linked to Behçet's disease and related clinical requests.
- HLA-DR4: A key marker for RA-related applications and a straightforward addition to your existing menu.
- HLA-B27: The most requested marker in rheumatology, strongly associated with ankylosing spondylitis and other spondyloarthropathies.
Run a broader HLA menu in one set-up
You can add new HLA markers without creating separate workflows or learning new protocols for each test. All Hola Biolabs HLA assays use the same lyophilized format, identical preparation steps, and same temperature profile.
- on your existing open qPCR instruments
- with MDX08 full automation
- with MDX01 in low-volume settings
Why portfolio expansion is easier with Hola Biolabs
Lyophilized reagent format
No reagent mixing, no cold chain, fewer preparation steps.
Same workflow across markers
All HLA assays share identical reagent format, preparation protocol, and temperature profile.
Automation as an option
Full automation option when you want minimal manual handling.
Compatible with existing PCR capability
Easy integration for labs that already have qPCR instruments and molecular experience.
Help with implementation
Practical support with assay validation, set-up, and routine operation.
Interested in Broadening Your In-House HLA Portfolio?
Let's discuss your current PCR set-up, the markers you want to add, and the most practical way to expand HLA testing in your laboratory.
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