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HLA Solutions

How to Broaden Your In-House HLA Portfolio

A practical route for laboratories already running PCR and looking to add relevant HLA markers in one set-up, with the option of full automation.

Why laboratories expand beyond HLA-B27

Many laboratories already running PCR offer only a limited HLA menu, often focused on HLA-B27. As clinical needs grow, this creates a gap between what the lab can deliver in-house and what clinicians request.

Hola Biolabs helps these laboratories expand their in-house HLA portfolio with lyophilized PCR kits that integrate easily into existing PCR set-ups or run with compact automation - without needing a completely new system for each marker.

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What becomes possible when the HLA portfolio grows

Expand beyond a basic HLA menu

Introduce additional markers in-house and build a wider HLA offer.

One laboratory set-up

Run multiple HLA markers within the same workflow instead of managing separate processes for each test.

Offer a broader HLA menu for rheumatology-related requests

Provide clinicians with a more complete HLA menu aligned with rheumatology needs.

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Key markers for portfolio expansion

  • HLA-DRB1 SE RA Risk Panel: A focused RA panel combining Shared Epitope, Valine 11, and DRB1*09:01 in one test.
  • HLA-B51: A useful addition for laboratories supporting testing linked to Behçet's disease and related clinical requests.
  • HLA-DR4: A key marker for RA-related applications and a straightforward addition to your existing menu.
  • HLA-B27: The most requested marker in rheumatology, strongly associated with ankylosing spondylitis and other spondyloarthropathies.
See the HLA Portfolio
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Run a broader HLA menu in one set-up

You can add new HLA markers without creating separate workflows or learning new protocols for each test. All Hola Biolabs HLA assays use the same lyophilized format, identical preparation steps, and same temperature profile.

  • on your existing open qPCR instruments
  • with MDX08 full automation
  • with MDX01 in low-volume settings
See Hola MDX Options
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Why portfolio expansion is easier with Hola Biolabs

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Lyophilized reagent format

No reagent mixing, no cold chain, fewer preparation steps.

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Same workflow across markers

All HLA assays share identical reagent format, preparation protocol, and temperature profile.

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Automation as an option

Full automation option when you want minimal manual handling.

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Compatible with existing PCR capability

Easy integration for labs that already have qPCR instruments and molecular experience.

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Help with implementation

Practical support with assay validation, set-up, and routine operation.

Available HLA PCR kits

All Hola Biolabs HLA kits use the same lyophilized format and temperature profile, making it straightforward to add new markers to your existing workflow.

HLA-DR4 PCR Kit HLA-DR4 PCR Kit
Lyophilized real-time SSP-PCR kit for qualitative detection of human HLA-DR4 (DRB1*04) alleles. Designed for HLA typing workflows with ambient-stable reagents and compatibility with selected open qPCR platforms or the Hola MDX08 System.
In stock
View HLA-DR4 PCR Kit
HLA-B51 PCR Kit HLA-B51 PCR Kit
Lyophilized real-time SSP-PCR kit for qualitative detection of human HLA-B51 alleles from DNA extracted from peripheral blood. Designed for HLA-B51 typing workflows related to Behçet’s disease research, with internal control and compatibility with selected open qPCR platforms or Hola MDX08 automation.
In stock
View HLA-B51 PCR Kit
HLA-B27 PCR Kit HLA-B27 PCR Kit
Lyophilized real-time SSP-PCR kit for qualitative detection of human HLA-B27 alleles. Designed for HLA typing workflows with ambient-stable reagents and compatibility with selected open qPCR platforms or the Hola MDX08 System.
In stock
View HLA-B27 PCR Kit
HLA-DRB1 Shared Epitope RA Risk Panel HLA-DRB1 Shared Epitope RA Risk Panel
Lyophilized PCR panel targeting key HLA-DRB1 markers associated with rheumatoid arthritis risk and severity, including Shared Epitope motifs, Val11, and DRB1*09:01.
Available on request / Contact us for availability.
View HLA-DRB1 Shared Epitope RA Risk Panel
HLA-B*58:01 PCR Kit HLA-B*58:01 PCR Kit
Lyophilized real-time PCR assay for qualitative detection of the HLA-B*58:01 allele, a pharmacogenetic marker associated with an increased risk of severe cutaneous adverse reactions to allopurinol.
Available on request / Contact us for availability.
View HLA-B*58:01 PCR Kit

Interested in Broadening Your In-House HLA Portfolio?

Let's discuss your current PCR set-up, the markers you want to add, and the most practical way to expand HLA testing in your laboratory.

Request Information
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